I am using the corsair void RGB wireless headset, all the time the game is in focus the mic doesn't work.
Otherwise, the mic works fine, it's a game related issue.
UPDATE After some troubleshooting I could not find the problem! Then Bam it hit me in the face, iCue Profile!
I create a custom iCue profile so I can have keymapping RGB on my K65 keyboard when I checked the headset, the mic recording level was zero! Cranked it up to 100 and all working.