I have a dual-monitor setup, with Insurgency playing on the left screen. When moving my mouse around in game, it seamlessly moves into the second monitor to the right. Then if I click somewhere on that second monitor Insurgency loses focus and I can't shoot or do anything until I click back into the window. This of course makes the game unplayable as long as I have the second monitor on as I'm constantly clicking outside the game while aiming. I have tried switching the video settings to windowed, borderless windowed, and fullscreen with no change in behavior.
Windows 10