Launching the game also launches SteamVR (if it's installed), but the game itself runs as normal.
Closing SteamVR doesn't force the game to close.
(As far as I know this is caused by Unreal Engine's VR support, the first game also had this kind of issue)
The game also opens on my secondary monitor instead of my primary monitor. (Primary monitor is #2, game opens on #1)